Liam McGuffin
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+44 (0) 118 378 6332
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Professor
- Admissions Tutor for BSc Biological Sciences with Industrial Experience
- Director of Impact and Enterprise
Teaching
- Part 1:
- The Living Cell
- Key Skills in Biological Sciences
- Building Blocks of Life
- Part 2:
- Molecular Biology of the Gene: Expression, Function and Analysis
- Molecular Genetics
- Protein Structure and Function
- Introduction to Bioinformatics and Computational Biology
- Professional Careers Development
- Part 3:
- Projects in Bioinformatics and Systems Biology
- MRes Biomedical Research
- MSc in Molecular Medicine
Research centres and groups
Member of the Impact, Enterprise and Outreach
- STEM Ambassador working with local secondary schools
- Science & Engineering Ambassador at Science Oxford for various events during National Science and Engineering Week and the Oxford Science Festival
- Scientific consultancy, software development and data mining work for various biotech companies
Research projects
- Funding from the BBSRC, MRC, Diamond Light Source, RCUK and International Governments
- Development of novel computational tools for the prediction of protein structures, functions and interactions from amino acid sequences. See: McGuffin Group Web servers
- Prediction and experimental verification of the effects of mutations on protein folding and function
- Application of computational methods for understanding the molecular mechanisms of cardiovascular function and disease
- Development of algorithms for the evaluation of the quality of 3D models of proteins and setting data standards for theoretical model validation
- High performance computing for the large scale structure and functional annotation of the proteomes of organisms relevant to food security
- Participation in the biennial experiments for the Critical Assessment of Techniques for Protein Structure Prediction (CASP)
Awards and honours
Esteem Factors
- RCUK Academic Fellowship (held from 2006-2011)
- Invited speaker at the 8th, 9th and 10th Community Wide Experiments on the Critical Assessment of Techniques for Protein Structure Prediction
- Member of the MRC College of Experts for Special Training Fellowships in Biomedical Informatics
- Member of the program committee for the European Conference on Computational Biology
Professional bodies/affiliations
International Collaborators
- Professor Dr Filiz Gurel, Istanbul University, Turkey
- Dr Luis V. Monteagudo, University of Zaragoza, Spain
- Dr Valter Tucci, Istituto Italiano di Tecnologia, Genova, Italy
- Dr Daniel Roche, The French National Sequencing Center (Genoscope), Évry, France
- Dr Carsten Pedersen, University of Copenhagen, Denmark
- Prof. Hans Thordal-Christensen University of Copenhagen, Denmark
- Prof. Ralph Panstruga, Max-Planck Institute for Plant Breeding Research, Cologne, Germany
- Dr Emiel Ver Loren van Themaat, Max-Planck Institute for Plant Breeding Research, Cologne, Germany
- Prof. Gerd Pfeifer, City of Hope National Medical Center, California, USA
- Dr Thomas Dunwell, City of Hope National Medical Center, California, USA
- Dr Paulo Teixeira, University of Campinas, Brazil
National Collaborators
- Dr Anne-Marie Mallon, MRC Harwell, Oxfordshire
- Dr Pat Nolan, MRC Harwell, Oxfordshire
- Dr Michelle Simon, MRC Harwell, Oxfordshire
- Dr Rohannah Hussain, Diamond Light Source, Oxfordshire
- Dr Laurence Bindschedler, Royal Holloway, University of London
- Dr Tim Burgis, Imperial College London
- Dr Pietro Spanu, Imperial College London
- Dr Kevin Bryson, University College London
- Dr Soren Sorensen, University College London
- Prof David T. Jones, University College London
- Prof Christine Oregno, University College London
- Prof Mike Sternberg, Imperial College London
- Prof Janet Thornton, European Bioinformatics Institute
- Lorenz Wernisch, University College London
- Dr Stefano Lise, University of Oxford
- Dr Michael Sadowski, Synthace, London